Pharmacological action – diuretic, potassium-sparing.
It is a competitive antagonist of aldosterone. In the distal renal tubules increases the excretion of sodium and water, reduces – potassium. Lowers blood pressure.
Indication of the drug Aldactone
Hyperaldosteronism (primary and idiopathic), diagnosis of hyperaldosteronism, adrenal adrenal gland producing aldosterone; Edematous syndrome with chronic heart failure, liver cirrhosis, nephrotic syndrome, nephropathy of pregnant women; Arterial hypertension, hypokalemia, as an adjuvant for malignant hypertension, hypokalemia, prevention of hypokalemia in patients receiving cardiac glycosides.
Hypersensitivity, anuria, renal failure (acute, chronic with a significant decrease in kidney function); Hyperkalaemia, pregnancy (I trimester).
Dyspepsia, diarrhea, headache, drowsiness, gynecomastia, decreased erections, menstrual disorders, menstrual bleeding in the climacteric period.
During treatment should avoid excessive intake of potassium in the body. It is not recommended to combine with other potassium-sparing diuretics. At simultaneous appointment with hypotensive and diuretic means it is necessary to reduce doses.